New research suggests a missing brain molecule may hold the key to understanding – and potentially treating – the faulty neural circuits seen in Down syndrome. Restoring the molecule, called ...

PHILADELPHIA (WPVI) -- Friday is World Down Syndrome Day. It is observed on March 21 to signify the uniqueness of the triplication of the 21 chromosome, which causes Down Syndrome. One way everyone is ...

After decades of mystery, researchers at Gladstone Institutes identify a gene that can derail heart formation—and show that fixing it prevents the problem in mice. SAN FRANCISCO—October 22, ...

Three copies of chromosome 21 cause Down syndrome (DS), and roughly half of children born each year in the United States with DS—approximately 2,600—also have congenital heart defects (CHDs).