The effect of leukoregulin, a 50-kD lymphokine with unique antitumor properties, was studied in vitro on several fibroblast functions. Leukoregulin did not inhibit fibroblast proliferation, as ...

FibroBiologics will present on fibroblast-based therapies for chronic diseases at a conference in Freiburg, Germany, on March 27, 2025. FibroBiologics, Inc., a biotechnology company focused on ...

Rare inherited diseases affect an estimated 3.5–5.9% of the global population, with most being genetically acquired and presenting in childhood. Despite their impact, these disorders remain poorly ...

The fibrous proteins and ground substance produced by fibroblasts are what constitute the extracellular matrix (ECM), which makes up the bulk of connective tissue. The ECM has many roles within ...

A new 3D connective tissue model gives researchers a sophisticated tool to understand the underlying mechanisms of connective tissue disorders and test potential treatments. To find treatments for ...

Engineering student research on joint damage, arthritis, heart problems, and tissue defects were the subject of presentations at a major national conference. Six students and researchers from the ...

Chimeric antigen receptor T (CAR-T) cell therapy has revolutionized hematologic cancer treatment, but its efficacy in solid tumors remains limited by poor infiltration into the complex tumor ...