Abbisko Therapeutics’ CSF-1R Inhibitor Pimicotinib Approved by the China NMPA, Addressing the Treatment Gap for Tenosynovial Giant Cell Tumor

Based on the positive global Phase III MANEUVER study, the National Medical Products Administration (NMPA) has granted the world’s first regulatory approval for pimicotinib, the first domestically ...
Business Insider

Arvinas Presents Late Breaking, Positive Phase 1 Clinical Data for ARV-102, a PROTAC LRRK2 Degrader, at the 2025 International Congress of Parkinson’s Disease and Movement ...

– ARV-102 was well tolerated in clinical trials for both healthy volunteers and patients with Parkinson’s disease – – ARV-102 demonstrated dose-dependent cerebrospinal fluid (CSF) exposure in subjects ...
Business Insider

Kiniksa Presents Preclinical Data on the GM-CSF Signaling Pathway in Temporal Arteries of GCA Patients at the Annual European Congress of Rheumatology

- Preclinical data support rationale for targeting GM-CSF in GCA – - Mavrilimumab showsbiological effect on genes relevant to GCA pathophysiology in ex vivo cultures of GCA arteries – HAMILTON, ...
Science Daily

New drug targets for Alzheimer's identified from cerebrospinal fluid

Researchers have linked disease-related proteins and genes to identify specific cellular pathways responsible for Alzheimer's genesis and progression. The proteins were gathered from cerebrospinal ...
Donga Science

Facial movements may stimulate newly discovered brain-clearing lymphatic pathways

The research team traced the CSF drainage pathways from the anterior and middle parts of the brain. Using genetically engineered mice that express fluorescent proteins in their lymphatic vessels, they ...